TITLE (PROF/DR/): PROF.

NAME: RAHMAT ADETUTU ADISA

POSITION: PROFESSOR                 SPECIALISATION: BIOMEMBRANES,   PHYTOMEDICINAL BIOCHEMISTRY AND TOXICOLOGY

EDUCATION/TRAINING (Begin with Bachelor’s degree or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

1. Personal Statement

Prof Adisa is a membrane biochemist with research interest in interrogating the role of mitochondrial structure and functional indices in diseases especially liver cancer and the possible mechanisms of mitochondrial targeted therapeutics for mitigating the symptoms and oxidative cellular damage. She is actively involved in some collaborative research involving mitochondria and hepatology and has published 47 publications in reputable journals in the area of mitochondrial toxicity, mechanistic actions of pharmacological agents and liver cancer based on her background training and expertise. She is a fellow of NIH/FIC D43 (2019 cohort) under the Emory-Nigeria Research Training Programme, and in 2020 under the Fogarty Bioethics training of the Centre for Bioethics. She recently completed an NIH/FIC D43 fellowship (D43TW010934) tagged the African Cancer Strategic Training Achievements for Research Success (STARS) program as a Principal Investigator. Rahmat is an NIH/FIC Emerging Global Leader Awardee (K43, 2023 – 2028) and has been a fellow of OWSD since 2005.  Her ultimate goal is to translate research outputs from her laboratory into diagnostic and prognostic biomarker products for early detection and treatment of hepatocellular cancer while building capacity to expand the frontiers of African science in mitochondrial research.

1. Positions, Scientific Appointments, and Honours

• NIH/FIC Emerging Global Leader Awardee (K43, 2023 – 2028)
• Member, Human Research Ethics Committee of College of Medicine, Unilag
• Fellow of ICMR/AU-STRC – 1^st Batch 2019
• Director and Board Member, HAVEK Leadership Academy (2019- Date)
• Member of Governing Council of Fountain University, Osogbo (November 2019 – 2022)
• Journal Reviewer (Elsevier Heliyon)

1. Selected Most Recent Publications /Contributions to Knowledge 

1. Kim K , Zheng Y, Joyce BT, Nannini DR, Wang J, Qu Y, Hawkins CA, Okeke E, Lesi OA, Lewis RR, Gursel DB, Abdulkareem FB, Akanmu AS, Duguru MJ, Davwar P, Nyam DP, Adisa RA, Imade G, Wei JJ, Kocherginsky M, Kim KY, Adeyemo WL, Odeghe E, Wehbe FH, Achenbach C, Sagay A, Ogunsola F, Murphy RL, Hou L. (2024). Cell-free DNA methylation-based inflammation score as a marker for hepatocellular carcinoma among people living with HIV. Hepatology International. Dec. DOI: 10.1007/s12072-024-10768-1. PMID: 39704909.
2. Adisa RA, Oluwole-Banjo K, Lawal RA, Bamiduro GJ, Abdulkareem FB. (2023) Annona senegalensis stem bark extracts attenuated doxorubicin-induced hepatotoxicity and mitochondrial oxidative damage in Wistar strain albino rats. Nig J Gastroenterology & Hepatology 15(2): 43-51
3. Ukwade CE, Ebuehi OAT, Adisa RA, Odukoya A, Agaba O, Adesegun SA, Igietseme JU, Omosun Y. (2022). Antioxidant and Cytototoxic Activities of Fractions of Ethanol Leaf Extract of Byrsocarpus coccineus And Thonn. (Connaraceae). European Journal of Applied Sciences. 10(4): 413 – 426
4. Ajibare CA., Ebuehi, OAT., Adisa RA., Sofidiya MO., Olugbuyiro JAO., Akinyede KA., Iyiola HA., Adegoke YA., Omoruyi SI., Ekpo OE. (2022). Fractions of Hoslundia opposite Vahl and Hoslundin-induced apoptosis in human cancer cells via mitochondrial-dependent reactive oxygen species (ROS) generation. Biomedicine & Pharmacotherapy. 153: 113475
5. Sulaimon L, Adisa R, Samuel T, Joel I, Ayankojo A, Abdulkareem F. Olajire O. (2021) “Molecular mechanism of mitoquinol mesylate in mitigating the progression of hepatocellular carcinoma- in silico and in vivo studies. Journal of Cellular Biochemistry 122(9): 1157-1172, http://doi.org/10.1002/jcb.29937

1. Collaborators/ Networks (International inclusive,

1. Ighovwerah, Department of Medicine, Division of Infectious Diseases, Emory University, Atlanta, USA.
2. Prof Lifang Hou, Northwestern University, Chicago, USA

• Prof Tim Rebbeck, Havard TH Chan School of Public Health & Dana Farber Cancer Institute, Boston, USA.

1. LA Sulaimon, Crescent University, Abeokuta, Ogun State, Nigeria